EAR23189.1 protein (Nitrococcus mobilis) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

EAR23189.1

DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (304 aa)

Predicted Functional Partners:

EAR23188.1

0.947

EAR23190.1

0.851

EAR22631.1

0.805

EAR22155.1

0.668

EAR22871.1

0.416

EAR22876.1

0.416

Your Current Organism:

Nitrococcus mobilis

NCBI taxonomy Id: 314278
Other names: N. mobilis Nb-231, Nitrococcus mobilis Nb-231, Nitrococcus mobilis str. Nb-231, Nitrococcus mobilis strain Nb-231

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAR22155.1	EAR22631.1	NB231_04580	NB231_09273	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.762
EAR22155.1	EAR22871.1	NB231_04580	NB231_10473	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416
EAR22155.1	EAR22876.1	NB231_04580	NB231_10498	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416
EAR22155.1	EAR23188.1	NB231_04580	NB231_15248	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.732
EAR22155.1	EAR23189.1	NB231_04580	NB231_15253	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.668
EAR22631.1	EAR22155.1	NB231_09273	NB231_04580	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.762
EAR22631.1	EAR22871.1	NB231_09273	NB231_10473	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416
EAR22631.1	EAR22876.1	NB231_09273	NB231_10498	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416
EAR22631.1	EAR23189.1	NB231_09273	NB231_15253	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.805
EAR22871.1	EAR22155.1	NB231_10473	NB231_04580	A protein.	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22871.1	EAR22631.1	NB231_10473	NB231_09273	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22871.1	EAR23188.1	NB231_10473	NB231_15248	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22871.1	EAR23189.1	NB231_10473	NB231_15253	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22876.1	EAR22155.1	NB231_10498	NB231_04580	A protein.	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22876.1	EAR22631.1	NB231_10498	NB231_09273	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22876.1	EAR23188.1	NB231_10498	NB231_15248	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR22876.1	EAR23189.1	NB231_10498	NB231_15253	A protein.	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.416
EAR23188.1	EAR22155.1	NB231_15248	NB231_04580	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	Resolvase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	0.732
EAR23188.1	EAR22871.1	NB231_15248	NB231_10473	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416
EAR23188.1	EAR22876.1	NB231_15248	NB231_10498	DNA invertase; COG1961 Site-specific recombinases, DNA invertase Pin homologs.	A protein.	0.416

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

9

average node degree:

3.6

avg. local clustering coefficient:

0.9

expected number of edges:

11

PPI enrichment p-value:

0.465

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:2001295

malonyl-CoA biosynthetic process

2 of 3

2.29

1.15

0.0073

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

7 of 89

1.36

1.73

3.18e-06

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 4

2.17

0.79

0.0348

GO:0003989

acetyl-CoA carboxylase activity

2 of 4

2.17

0.79

0.0348

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009317

acetyl-CoA carboxylase complex

2 of 3

2.29

1.3

0.0038

GO:0005737

Cytoplasm

11 of 1119

0.46

0.38

0.00095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2244

Mixed, incl. The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules., and Peroxiredoxin activity

4 of 6

2.29

2.56

1.08e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01210

2-Oxocarboxylic acid metabolism

4 of 22

1.73

1.76

0.00012

map00300

Lysine biosynthesis

4 of 24

1.69

1.73

0.00012

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 4

2.17

0.75

0.0419

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0805

Transcription regulation

7 of 113

1.26

1.52

4.72e-06

KW-0238

DNA-binding

7 of 190

1.04

4.98e-05

KW-0275

Fatty acid biosynthesis

2 of 11

1.73

0.71

0.0408

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01039

Carboxyl transferase domain

2 of 2

2.47

0.83

0.0302

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

7 of 12

2.23

5.3

2.51e-12

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

4 of 5

2.37

3.23

5.11e-07

SM00895

This entry represents the C-terminal ligand binding domain of many members of the GntR family. This domain probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N-terminal DNA-binding ...

2 of 3

2.29

1.29

0.0040

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