node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGH80326.1 | argH | PCNPT3_01920 | PCNPT3_01685 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | 0.402 |
AGH80326.1 | proA | PCNPT3_01920 | PCNPT3_10130 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.936 |
AGH80326.1 | proB | PCNPT3_01920 | PCNPT3_10135 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.938 |
AGH80326.1 | proC | PCNPT3_01920 | PCNPT3_01575 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.954 |
AGH80326.1 | tyrA | PCNPT3_01920 | PCNPT3_02445 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Bifunctional chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. | 0.497 |
AGH80774.1 | proA | PCNPT3_04160 | PCNPT3_10130 | DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.544 |
AGH80774.1 | proB | PCNPT3_04160 | PCNPT3_10135 | DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.534 |
AGH80774.1 | proC | PCNPT3_04160 | PCNPT3_01575 | DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.546 |
argH | AGH80326.1 | PCNPT3_01685 | PCNPT3_01920 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.402 |
argH | proA | PCNPT3_01685 | PCNPT3_10130 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.599 |
argH | proB | PCNPT3_01685 | PCNPT3_10135 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.599 |
argH | proC | PCNPT3_01685 | PCNPT3_01575 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.596 |
argH | serC | PCNPT3_01685 | PCNPT3_03335 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.441 |
argH | thrA | PCNPT3_01685 | PCNPT3_03780 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Bifunctional aspartokinase I/homoserine dehydrogenase I; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.626 |
argH | tyrA | PCNPT3_01685 | PCNPT3_02445 | Bifunctional argininosuccinate lyase/N-acetylglutamate synthase; COG0165 Argininosuccinate lyase. | Bifunctional chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. | 0.544 |
crl | frsA | PCNPT3_10140 | PCNPT3_10145 | DNA-binding transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Fermentation/respiration switch protein; COG1073 Hydrolases of the alpha/beta superfamily; Belongs to the UPF0255 family. | 0.906 |
crl | proA | PCNPT3_10140 | PCNPT3_10130 | DNA-binding transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.471 |
crl | proB | PCNPT3_10140 | PCNPT3_10135 | DNA-binding transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.577 |
frsA | crl | PCNPT3_10145 | PCNPT3_10140 | Fermentation/respiration switch protein; COG1073 Hydrolases of the alpha/beta superfamily; Belongs to the UPF0255 family. | DNA-binding transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.906 |
frsA | proA | PCNPT3_10145 | PCNPT3_10130 | Fermentation/respiration switch protein; COG1073 Hydrolases of the alpha/beta superfamily; Belongs to the UPF0255 family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.417 |