STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR08724.1COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (306 aa)    
Predicted Functional Partners:
EAR09677.1
Superfamily II DNA/RNA helicase, SNF2 family protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 0.921
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
    
 0.900
EAR07363.1
COG2319 FOG: WD40 repeat.
    
 0.862
EAR10265.1
Hypothetical protein; COG1033 Predicted exporters of the RND superfamily.
    
 0.862
EAR10085.1
Ankyrin-related protein; COG0666 FOG: Ankyrin repeat.
   
 0.822
EAR08367.1
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.782
atpD
ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
 0.745
mutS
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 
 0.726
udk
COG0572 Uridine kinase.
   
 0.665
EAR08726.1
Hypothetical protein.
   
 0.629
Your Current Organism:
Reinekea blandensis
NCBI taxonomy Id: 314283
Other names: R. blandensis MED297, Reinekea blandensis MED297, Reinekea blandensis str. MED297, Reinekea blandensis strain MED297, Reinekea sp. MED297
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.