STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR08198.1COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (521 aa)    
Predicted Functional Partners:
EAR08520.1
COG2374 Predicted extracellular nuclease.
  
 0.950
EAR08654.1
Hypothetical protein; COG2374 Predicted extracellular nuclease.
  
 0.947
EAR08978.1
Alkaline phosphatase-like protein; COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.
 
   
  0.935
nudC
NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
    
  0.892
deoD
COG0813 Purine-nucleoside phosphorylase.
    
 0.889
guaB
Inositol-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.884
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
    
 0.866
udk
COG0572 Uridine kinase.
 
 
 0.859
tdk
COG1435 Thymidine kinase.
 
  
  0.840
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
   
  0.831
Your Current Organism:
Reinekea blandensis
NCBI taxonomy Id: 314283
Other names: R. blandensis MED297, Reinekea blandensis MED297, Reinekea blandensis str. MED297, Reinekea blandensis strain MED297, Reinekea sp. MED297
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.