node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR07454.1 | EAR09379.1 | MED297_05044 | MED297_02127 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.931 |
EAR07454.1 | guaA | MED297_05044 | MED297_15030 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.645 |
EAR07454.1 | rlmL | MED297_05044 | MED297_16594 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.656 |
EAR07454.1 | rpoC | MED297_05044 | MED297_06788 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.929 |
EAR07454.1 | thiI | MED297_05044 | MED297_12577 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.968 |
EAR07454.1 | trmA | MED297_05044 | MED297_16564 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.526 |
EAR07454.1 | trmB | MED297_05044 | MED297_10601 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.806 |
EAR07454.1 | trmH | MED297_05044 | MED297_02377 | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Putative tRNA methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.460 |
EAR08370.1 | trmA | MED297_16559 | MED297_16564 | tRNA-(ms[2]io[6]A)-hydroxylase; COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.614 |
EAR09379.1 | EAR07454.1 | MED297_02127 | MED297_05044 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.931 |
EAR09379.1 | guaA | MED297_02127 | MED297_15030 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.772 |
EAR09379.1 | rpoC | MED297_02127 | MED297_06788 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.989 |
EAR09379.1 | trmA | MED297_02127 | MED297_16564 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.531 |
EAR09379.1 | trmB | MED297_02127 | MED297_10601 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.438 |
EAR09379.1 | trmH | MED297_02127 | MED297_02377 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Putative tRNA methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.595 |
dusC | guaA | MED297_13597 | MED297_15030 | NifR3/Smm1 family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.565 |
dusC | trmA | MED297_13597 | MED297_16564 | NifR3/Smm1 family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.621 |
dusC | trmB | MED297_13597 | MED297_10601 | NifR3/Smm1 family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.507 |
guaA | EAR07454.1 | MED297_15030 | MED297_05044 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.645 |
guaA | EAR09379.1 | MED297_15030 | MED297_02127 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.772 |