STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR07647.1Aconitate hydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family. (861 aa)    
Predicted Functional Partners:
EAR09632.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.978
EAR09656.1
COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.957
EAR11422.1
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
   
 
 0.954
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.951
EAR08692.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.930
EAR09064.1
COG2224 Isocitrate lyase.
     
 0.924
prpB
PEP phosphonomutase and related enzyme; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.901
EAR08694.1
COG2828 Uncharacterized protein conserved in bacteria.
    
 0.894
EAR08693.1
Aconitate hydratase; COG1048 Aconitase A.
    
 0.892
EAR10702.1
COG0039 Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily.
  
  
 0.884
Your Current Organism:
Reinekea blandensis
NCBI taxonomy Id: 314283
Other names: R. blandensis MED297, Reinekea blandensis MED297, Reinekea blandensis str. MED297, Reinekea blandensis strain MED297, Reinekea sp. MED297
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