node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR08473.1 | EAR08474.1 | MED297_17812 | MED297_17817 | COG1286 Uncharacterized membrane protein, required for colicin V production. | COG3147 Uncharacterized protein conserved in bacteria. | 0.714 |
EAR08473.1 | EAR08475.1 | MED297_17812 | MED297_17822 | COG1286 Uncharacterized membrane protein, required for colicin V production. | FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase. | 0.652 |
EAR08473.1 | EAR08919.1 | MED297_17812 | MED297_04597 | COG1286 Uncharacterized membrane protein, required for colicin V production. | COG3087 Cell division protein. | 0.641 |
EAR08473.1 | EAR09674.1 | MED297_17812 | MED297_15984 | COG1286 Uncharacterized membrane protein, required for colicin V production. | COG0670 Integral membrane protein, interacts with FtsH; Belongs to the BI1 family. | 0.721 |
EAR08473.1 | EAR11374.1 | MED297_17812 | MED297_20842 | COG1286 Uncharacterized membrane protein, required for colicin V production. | Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.724 |
EAR08473.1 | purC | MED297_17812 | MED297_13907 | COG1286 Uncharacterized membrane protein, required for colicin V production. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.845 |
EAR08473.1 | purE | MED297_17812 | MED297_05674 | COG1286 Uncharacterized membrane protein, required for colicin V production. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.812 |
EAR08473.1 | purF | MED297_17812 | MED297_17807 | COG1286 Uncharacterized membrane protein, required for colicin V production. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.976 |
EAR08473.1 | purL | MED297_17812 | MED297_03275 | COG1286 Uncharacterized membrane protein, required for colicin V production. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.981 |
EAR08473.1 | purM | MED297_17812 | MED297_16983 | COG1286 Uncharacterized membrane protein, required for colicin V production. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.832 |
EAR08474.1 | EAR08473.1 | MED297_17817 | MED297_17812 | COG3147 Uncharacterized protein conserved in bacteria. | COG1286 Uncharacterized membrane protein, required for colicin V production. | 0.714 |
EAR08474.1 | EAR08475.1 | MED297_17817 | MED297_17822 | COG3147 Uncharacterized protein conserved in bacteria. | FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase. | 0.916 |
EAR08474.1 | EAR08919.1 | MED297_17817 | MED297_04597 | COG3147 Uncharacterized protein conserved in bacteria. | COG3087 Cell division protein. | 0.478 |
EAR08474.1 | EAR11374.1 | MED297_17817 | MED297_20842 | COG3147 Uncharacterized protein conserved in bacteria. | Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.533 |
EAR08474.1 | purF | MED297_17817 | MED297_17807 | COG3147 Uncharacterized protein conserved in bacteria. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.660 |
EAR08475.1 | EAR08473.1 | MED297_17822 | MED297_17812 | FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase. | COG1286 Uncharacterized membrane protein, required for colicin V production. | 0.652 |
EAR08475.1 | EAR08474.1 | MED297_17822 | MED297_17817 | FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase. | COG3147 Uncharacterized protein conserved in bacteria. | 0.916 |
EAR08475.1 | purF | MED297_17822 | MED297_17807 | FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.814 |
EAR08919.1 | EAR08473.1 | MED297_04597 | MED297_17812 | COG3087 Cell division protein. | COG1286 Uncharacterized membrane protein, required for colicin V production. | 0.641 |
EAR08919.1 | EAR08474.1 | MED297_04597 | MED297_17817 | COG3087 Cell division protein. | COG3147 Uncharacterized protein conserved in bacteria. | 0.478 |