node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR11229.1 | EAR11230.1 | MED297_20117 | MED297_20122 | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | ParA family protein; COG1192 ATPases involved in chromosome partitioning. | 0.999 |
EAR11229.1 | mnmE | MED297_20117 | MED297_05779 | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.620 |
EAR11229.1 | mnmG | MED297_20117 | MED297_20132 | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.856 |
EAR11229.1 | rsmG | MED297_20117 | MED297_20127 | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.968 |
EAR11230.1 | EAR11229.1 | MED297_20122 | MED297_20117 | ParA family protein; COG1192 ATPases involved in chromosome partitioning. | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | 0.999 |
EAR11230.1 | mnmG | MED297_20122 | MED297_20132 | ParA family protein; COG1192 ATPases involved in chromosome partitioning. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.804 |
EAR11230.1 | rsmG | MED297_20122 | MED297_20127 | ParA family protein; COG1192 ATPases involved in chromosome partitioning. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.940 |
era | mnmE | MED297_00895 | MED297_05779 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.910 |
era | rpsF | MED297_00895 | MED297_14535 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.991 |
era | rsmG | MED297_00895 | MED297_20127 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.584 |
groL | rsmG | MED297_02692 | MED297_20127 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.687 |
groL | yidC | MED297_02692 | MED297_05774 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.457 |
mnmE | EAR11229.1 | MED297_05779 | MED297_20117 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | 0.620 |
mnmE | era | MED297_05779 | MED297_00895 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.910 |
mnmE | mnmG | MED297_05779 | MED297_20132 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.995 |
mnmE | rnpA | MED297_05779 | MED297_05769 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.755 |
mnmE | rsmG | MED297_05779 | MED297_20127 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.919 |
mnmE | yidC | MED297_05779 | MED297_05774 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.916 |
mnmG | EAR11229.1 | MED297_20132 | MED297_20117 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | ParB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | 0.856 |
mnmG | EAR11230.1 | MED297_20132 | MED297_20122 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | ParA family protein; COG1192 ATPases involved in chromosome partitioning. | 0.804 |