| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ97543.1 | EAQ97544.1 | KT71_04520 | KT71_04525 | Hypothetical protein. | Transcriptional regulator, AsnC family. | 0.511 |
| EAQ97543.1 | leuA | KT71_04520 | KT71_04515 | Hypothetical protein. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.533 |
| EAQ97544.1 | EAQ97543.1 | KT71_04525 | KT71_04520 | Transcriptional regulator, AsnC family. | Hypothetical protein. | 0.511 |
| EAQ97544.1 | EAQ99417.1 | KT71_04525 | KT71_17146 | Transcriptional regulator, AsnC family. | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | 0.463 |
| EAQ97544.1 | birA | KT71_04525 | KT71_01260 | Transcriptional regulator, AsnC family. | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.445 |
| EAQ97544.1 | cysG | KT71_04525 | KT71_15866 | Transcriptional regulator, AsnC family. | uroporphyrinogen-III C-methyltransferase/precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.739 |
| EAQ97544.1 | leuA | KT71_04525 | KT71_04515 | Transcriptional regulator, AsnC family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.565 |
| EAQ99417.1 | EAQ97544.1 | KT71_17146 | KT71_04525 | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | Transcriptional regulator, AsnC family. | 0.463 |
| EAQ99417.1 | birA | KT71_17146 | KT71_01260 | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.801 |
| EAQ99417.1 | leuA | KT71_17146 | KT71_04515 | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.790 |
| birA | EAQ97544.1 | KT71_01260 | KT71_04525 | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Transcriptional regulator, AsnC family. | 0.445 |
| birA | EAQ99417.1 | KT71_01260 | KT71_17146 | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | 0.801 |
| birA | cysG | KT71_01260 | KT71_15866 | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | uroporphyrinogen-III C-methyltransferase/precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.696 |
| cysG | EAQ97544.1 | KT71_15866 | KT71_04525 | uroporphyrinogen-III C-methyltransferase/precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Transcriptional regulator, AsnC family. | 0.739 |
| cysG | birA | KT71_15866 | KT71_01260 | uroporphyrinogen-III C-methyltransferase/precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.696 |
| leuA | EAQ97543.1 | KT71_04515 | KT71_04520 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Hypothetical protein. | 0.533 |
| leuA | EAQ97544.1 | KT71_04515 | KT71_04525 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Transcriptional regulator, AsnC family. | 0.565 |
| leuA | EAQ99417.1 | KT71_04515 | KT71_17146 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta). | 0.790 |