STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
EAQ97131.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; And related enzymes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (714 aa)    
Predicted Functional Partners:
EAQ97386.1
Glutamate synthase (NADPH) large subunit.
    
 0.934
EAQ99278.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.930
EAQ98333.2
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.925
EAQ98334.1
Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.917
gcvP
Glycine dehydrogenase alpha subunit/glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 0.910
EAQ99279.1
2-oxoglutarate dehydrogenase, E1 component.
  
 0.877
EAQ95995.1
Malic enzyme.
  
 
 0.824
EAQ96877.1
NADH:flavin oxidoreductase, Old Yellow Enzyme family.
 
 0.807
EAQ97132.2
Putative endonuclease; Containing a URI domain.
       0.784
EAQ99121.1
Hypothetical protein; TIGR01244.
  
 0.770
Your Current Organism:
Congregibacter litoralis
NCBI taxonomy Id: 314285
Other names: C. litoralis KT71, Congregibacter litoralis KT71, Congregibacter litoralis str. KT71, Congregibacter litoralis strain KT71, gamma proteobacterium KT71, unknown marine gamma proteobacterium NOR5
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