Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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EAQ95840.2Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.997
EAQ99281.2
Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.994
EAQ96070.1
Succinate dehydrogenase subunit A.
  
 
 0.988
EAQ99284.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.987
gcvP
Glycine dehydrogenase alpha subunit/glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.987
EAQ99280.1
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.981
EAQ96071.1
Succinate dehydrogenase subunit B.
  
 
 0.979
EAQ99282.2
Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.979
EAQ96376.1
Fumarase, class II.
  
 
 0.968
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.967
Your Current Organism:
Congregibacter litoralis
NCBI taxonomy Id: 314285
Other names: C. litoralis KT71, Congregibacter litoralis KT71, Congregibacter litoralis str. KT71, Congregibacter litoralis strain KT71, gamma proteobacterium KT71, unknown marine gamma proteobacterium NOR5
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