node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAS46001.1 | EAS46517.1 | GB2207_07382 | GB2207_06683 | Probable iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 0.870 |
EAS46517.1 | EAS46001.1 | GB2207_06683 | GB2207_07382 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Probable iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.870 |
EAS46517.1 | EAS46605.1 | GB2207_06683 | GB2207_07123 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | 0.911 |
EAS46517.1 | EAS46607.1 | GB2207_06683 | GB2207_07133 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | 0.918 |
EAS46517.1 | EAS47492.1 | GB2207_06683 | GB2207_01772 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Hypothetical protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.915 |
EAS46517.1 | clpB | GB2207_06683 | GB2207_05629 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.915 |
EAS46517.1 | dnaJ | GB2207_06683 | GB2207_10713 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.950 |
EAS46517.1 | groEL | GB2207_06683 | GB2207_11803 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.871 |
EAS46517.1 | grpE | GB2207_06683 | GB2207_10703 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.981 |
EAS46517.1 | htpG | GB2207_06683 | GB2207_02452 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.980 |
EAS46517.1 | rplP | GB2207_06683 | GB2207_06173 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.886 |
EAS46605.1 | EAS46517.1 | GB2207_07123 | GB2207_06683 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 0.911 |
EAS46605.1 | EAS47492.1 | GB2207_07123 | GB2207_01772 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.693 |
EAS46605.1 | clpB | GB2207_07123 | GB2207_05629 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.693 |
EAS46605.1 | groEL | GB2207_07123 | GB2207_11803 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.809 |
EAS46605.1 | grpE | GB2207_07123 | GB2207_10703 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.921 |
EAS46605.1 | htpG | GB2207_07123 | GB2207_02452 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.895 |
EAS46605.1 | rplP | GB2207_07123 | GB2207_06173 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.625 |
EAS46607.1 | EAS46517.1 | GB2207_07133 | GB2207_06683 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 0.918 |
EAS46607.1 | EAS47492.1 | GB2207_07133 | GB2207_01772 | curved-DNA-binding protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.693 |