STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAS48005.1COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. (595 aa)    
Predicted Functional Partners:
EAS46458.1
General secretion pathway protein F; COG1459 Type II secretory pathway, component PulF.
 
 0.942
EAS47289.1
Pilin secretion/fimbrial assembly system protein, PilC; COG1459 Type II secretory pathway, component PulF.
 
 0.942
EAS46457.1
Putative general secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
  
 
0.896
EAS46464.1
General secretion pathway protein L; COG3297 Type II secretory pathway, component PulL.
  
 
 0.872
EAS47288.1
Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.833
EAS46459.1
General secretion pathway protein G; COG2165 Type II secretory pathway, pseudopilin PulG.
 
 0.823
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
       0.776
EAS46888.1
COG3166 Tfp pilus assembly protein PilN.
   
 
 0.715
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
       0.709
EAS47443.1
Type 4 fimbrial biogenesis protein PilZ; COG3215 Tfp pilus assembly protein PilZ.
    
   0.707
Your Current Organism:
gamma proteobacterium HTCC2207
NCBI taxonomy Id: 314287
Other names: g. proteobacterium HTCC2207, marine gamma proteobacterium HTCC2207
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