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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0055Putative thiamine/thiamine precursor:cation symporter. (388 aa)    
Predicted Functional Partners:
thiM
Hydroxyethylthiazole kinase (4-methyl-5-beta-hydroxyethylthiazole kinase); Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
    0.909
thiE
Thiamine-phosphate pyrophosphorylase (Thiamine-phosphate synthase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.863
thiD
Phosphomethylpyrimidine kinase (HMP-phosphate kinase).
  
  
 0.836
pyrB
Aspartate carbamoyltransferase (Asparate transcarbamylase); Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
    0.487
pyrAB
Carbamoyl-phosphate synthase, catalytic subunit.
   
    0.476
pyrAA
Carbamoyl-phosphate synthase, glutaminase subunit; Belongs to the CarA family.
   
    0.472
LCA_0199
5 Proteins of unknown function that are similar to other proteins.
  
     0.400
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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