| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | gmk1 | LCA_1276 | LCA_0107 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase. | 0.935 |
| apt | gmk2 | LCA_1276 | LCA_0685 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.932 |
| apt | guaA | LCA_1276 | LCA_0139 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine monophosphate synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP. | 0.989 |
| apt | guaC | LCA_1276 | LCA_0476 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine 5'-monophosphate reductase (GMP reductase); Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.963 |
| apt | hpt | LCA_1276 | LCA_1598 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltranferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.942 |
| apt | xpt | LCA_1276 | LCA_1557 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.949 |
| gmk1 | apt | LCA_0107 | LCA_1276 | Guanylate kinase. | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.935 |
| gmk1 | gmk2 | LCA_0107 | LCA_0685 | Guanylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
| gmk1 | guaA | LCA_0107 | LCA_0139 | Guanylate kinase. | Guanosine monophosphate synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP. | 0.956 |
| gmk1 | guaC | LCA_0107 | LCA_0476 | Guanylate kinase. | Guanosine 5'-monophosphate reductase (GMP reductase); Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.909 |
| gmk1 | hpt | LCA_0107 | LCA_1598 | Guanylate kinase. | Hypoxanthine phosphoribosyltranferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
| gmk1 | nrdE | LCA_0107 | LCA_0941 | Guanylate kinase. | Ribonucleoside-diphosphate reductase, alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.910 |
| gmk1 | nrdF | LCA_0107 | LCA_0940 | Guanylate kinase. | Ribonucleoside-diphosphate reductase, beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.903 |
| gmk1 | pyk | LCA_0107 | LCA_1032 | Guanylate kinase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.931 |
| gmk1 | relA | LCA_0107 | LCA_0737 | Guanylate kinase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
| gmk1 | xpt | LCA_0107 | LCA_1557 | Guanylate kinase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.934 |
| gmk2 | apt | LCA_0685 | LCA_1276 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.932 |
| gmk2 | gmk1 | LCA_0685 | LCA_0107 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanylate kinase. | 0.926 |
| gmk2 | guaA | LCA_0685 | LCA_0139 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine monophosphate synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP. | 0.961 |
| gmk2 | guaC | LCA_0685 | LCA_0476 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine 5'-monophosphate reductase (GMP reductase); Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.909 |
STRING v12.5 is now available!
