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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0146Putative adenine-specifique DNA methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (261 aa)    
Predicted Functional Partners:
lexA
Transcriptional repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.904
LCA_0143
Putative adenine-specific DNA methyltransferase.
 
  
 0.860
tnpB1-IS1520
Transposase (orfB) of IS1520 (IS3 family).
       0.530
tnpA1-IS1520
Transposase (orfA) of IS1520 (IS3 family).
       0.528
LCA_0142
5 Proteins of unknown function that are similar to other proteins.
 
     0.522
guaA
Guanosine monophosphate synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
       0.505
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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