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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0230Putative transcriptional regulator, MerR family (C-terminal fragment), authentic frameshift. (81 aa)    
Predicted Functional Partners:
LCA_0227
Putative drug:H(+) antiporter.
 
    0.892
LCA_0228
5 Proteins of unknown function that are similar to other proteins.
 
    0.851
LCA_0229
Putative transcriptional regulator, MerR family (N-terminal fragment), authentic frameshift.
       0.773
dnaJ
Chaperone protein DnaJ (heat-shock protein Hsp40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.544
lmrA
Multidrug ABC exporter, ATP-binding and membrane-spanning/permease subunits.
  
    0.528
LCA_0231
Putative transcriptional regulator, MarR family.
       0.526
pepN
Aminopeptidase N (Lysyl-aminopeptidase-Alanyl aminopeptidase).
       0.514
glnA
Glutamate--ammonia ligase (Glutamine synthetase).
  
 
 0.477
LCA_0808
Putative amino acid export protein.
  
     0.446
sigA
DNA-directed RNA polymerase sigma factor, sigma A (Primary sigma factor); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.443
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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