close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0403Putative thioredoxin reductase. (328 aa)    
Predicted Functional Partners:
LCA_0402
Iron(III)-compound ABC transporter, membrane-spanning subunit; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.829
LCA_0401
Iron(III)-compound ABC transporter, membrane-spanning subunit; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.827
LCA_0400
Iron(III)-compound ABC transporter, ATP-binding subunit.
  
    0.813
LCA_0399
Iron(III)-compound ABC transporter, substrate-binding lipoprotein precursor.
  
    0.640
metS
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
 
 0.570
adhE
Bifunctional enzyme: alcohol dehydrogenase, acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.508
trxA1
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.454
trxA2
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.454
trxA3
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.454
LCA_0090
Putative extracellular arylsulfate sulfotransferase (N-terminal fragment), authentic frameshift.
  
 
 0.453
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
Server load: low (20%) [HD]