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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0484Putative oxidoreductase, short-chain dehydrogenase/reductase family. (243 aa)    
Predicted Functional Partners:
fabD
Malonyl-CoA:ACP transacylase.
 0.967
fabF
3-oxoacyl-[acyl carrier protein] synthetase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.960
fabZ1
(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase.
  
 0.936
fabZ2
(3R)-hydroxymyristoyl-[acyl carrier proetin] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 0.936
fabH
3-oxoacyl-[acyl carrier protein] synthetase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.933
fabG
3-oxoacyl-acyl carrier protein reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.923
LCA_0454
Putative oxidoreductase, short-chain dehydrogenase/reductase family.
  
  
 
0.920
fabI
Enoyl [acyl carrier protein] reductase.
  
 
 0.919
LCA_0482
5 Proteins of unknown function that are similar to other proteins.
   
   0.866
LCA_0483
5 Proteins of unknown function that are similar to other proteins.
   
   0.866
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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