STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0525Hypothetical integral membrane protein. (178 aa)    
Predicted Functional Partners:
uvrA1
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
    0.589
LCA_0526
Hypothetical protein; Displays ATPase and GTPase activities.
       0.583
LCA_0527
Putative extracellular lipase/esterase precursor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
       0.583
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
       0.583
uvrB
Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.569
LCA_1698
Hypothetical integral membrane protein.
  
  
 0.523
LCA_1003
5 Proteins of unknown function that are similar to other proteins.
  
     0.495
LCA_1412
Putative lipase/esterase.
  
     0.426
LCA_0806
Putative N-acetyl transferase, GNAT family.
  
     0.424
LCA_0529
Putative transcriptional regulator, MarR family.
       0.423
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.