close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0549Two-component system, response regulator. (201 aa)    
Predicted Functional Partners:
LCA_0548
Two-component system, sensor histidine kinase (C-terminal fragment), authentic frameshift.
 
 0.997
LCA_0545
Putative drug ABC exporter, membrane-spanning subunit.
 
  
 0.960
LCA_0544
Putative drug ABC exporter, ATP-binding subunit.
  
 0.951
LCA_1370
Two-component system, sensor histidine kinase.
 
 0.931
LCA_0547
Two-component system, sensor histidine kinase (N-terminal fragment), authentic frameshift.
  
 
 0.911
LCA_0546
6 Protein of unknown function, without similarity to other proteins.
  
 
 0.900
LCA_0550
6 Protein of unknown function, without similarity to other proteins.
       0.605
LCA_0253
Putative transcriptional regulator with a sugar kinase domain, GntR family.
  
 
 0.542
LCA_0254
Putative carbohydrate kinase.
  
 
 0.542
LCA_0690
Putative rRNA methytransferase (sun protein); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.526
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
Server load: low (24%) [HD]