close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppRTwo-component system, response regulator SppR (sakacin P production). (248 aa)    
Predicted Functional Partners:
sppKC
Two-component system, sensor histidine kinase (SppK fragment) (sakacine Pproduction), degenerate.
 
 
 0.980
LCA_1501
Two-component system, sensor histidine kinase.
     
 0.901
sppKN
Two-component system, sensor histidine kinase, (SppK fragment) (sakacine P production), degenerate.
  
 
 0.885
mreB
Cell shape determining protein MreB, actin-like.
   
 
 0.690
LCA_1820
Hypothetical cell surface protein precursor.
  
     0.685
LCA_0434
Hypothetical membrane protein.
     
 0.667
LCA_0293
Putative DNA-binding protein, XRE family.
  
     0.625
CAI54867.1
Putative bacteriocin Immunity protein.
     
 0.608
LCA_1383
Two-component system, sensor histidine kinase.
  
 
 0.551
LCA_1455
Two-component system, sensor histidine kinase.
  
 
 0.551
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.