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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmUtRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (379 aa)    
Predicted Functional Partners:
LCA_0790
Hypothetical protein, ATP utilizing enzyme PP-loop family.
    
 0.870
LCA_0791
Putative cysteine desulfurase (aminotransferase, class V).
  
  
 0.751
thiI
Thiamine biosynthesis ATP pyrophosphorylase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.719
LCA_1241
Bifunctional enzyme, riboflavin kinase and FMN adenylyltransferase; Belongs to the ribF family.
 
    0.693
LCA_0792
5 Proteins of unknown function that are similar to other proteins.
       0.690
metS
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.668
LCA_0690
Putative rRNA methytransferase (sun protein); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.602
recD
Exodeoxyribonuclease V, alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
    0.597
gpm4
Phosphoglycerate mutase.
  
    0.594
ddl
D-alanine--D-alanine ligase (D-alanylalanine synthetase); Cell wall formation.
  
  
 0.585
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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