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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_0851Putative hydrolase, haloacid dehalogenase family. (207 aa)    
Predicted Functional Partners:
folC1
Putative polylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
    0.789
radC
DNA repair protein (RadC); Belongs to the UPF0758 family.
       0.634
valS
Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.605
LCA_0274
Putative DNA helicase (N-terminal fragment), authentic frameshift.
 
      0.522
nagE
N-acetylglucosamine and glucose-specific phosphotransferase system, enzyme IIABC.
  
  
 0.505
LCA_1198
Putative trehalose and glucose-specific phosphotransferase system, enzyme EIIA.
  
  
 0.505
LCA_1200
Putative trehalose and glucose-specific phosphotransferase system, enzyme IIBC.
  
  
 0.505
scrA
Sucrose-specific phosphotransferase system, enzyme IIBCA.
  
  
 0.505
rex-2
Hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.499
pdhA
Pyruvate dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
    0.437
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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