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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_09625 Proteins of unknown function that are similar to other proteins. (166 aa)    
Predicted Functional Partners:
LCA_0963
Integral membrane protein, hemolysin III related.
 
  
 0.715
LCA_1536
5 Proteins of unknown function that are similar to other proteins.
  
     0.631
LCA_1335
Hypothetical membrane protein.
  
     0.557
LCA_0964
Hypothetical protein, DegV family.
       0.538
dnaJ
Chaperone protein DnaJ (heat-shock protein Hsp40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.536
LCA_0429
Putative phosphoesterase.
  
     0.510
LCA_1379
Putative metal-dependent phosphohydrolase.
 
 
   0.500
glnA
Glutamate--ammonia ligase (Glutamine synthetase).
  
 
 0.456
LCA_1663
5 Proteins of unknown function that are similar to other proteins.
  
     0.444
sigA
DNA-directed RNA polymerase sigma factor, sigma A (Primary sigma factor); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.431
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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