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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_10475 Proteins of unknown function that are similar to other proteins. (364 aa)    
Predicted Functional Partners:
LCA_0353
Putative cellobiose-specific phosphotransferase system, enzyme IIB.
 
     0.781
LCA_1533
Putative cellobiose-specific phosphotransferasesystem, enzyme IIA.
 
    0.777
LCA_1457
Putative cellobiose-specific phosphotransferase system, enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
  
 0.752
LCA_1690
Putative cellobiose-specific phosphotransferasesystem, enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
  
 0.736
LCA_1542
Putative phosphotransferase system, enzyme IIC (C-terminal fragment), authentic frameshift.
 
  
 0.587
LCA_1200
Putative trehalose and glucose-specific phosphotransferase system, enzyme IIBC.
 
     0.572
LCA_0300
5 Proteins of unknown function that are similar to other proteins.
 
    0.523
obg
Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.518
fruR
Fructose operon transcription regulator, DeoR family.
       0.515
fruK
1-phosphofructokinase (fructose-1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
       0.515
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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