close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruRFructose operon transcription regulator, DeoR family. (250 aa)    
Predicted Functional Partners:
fruA
Fructose-specific phosphotransferase system, enzyme IIABC.
 
  
 0.997
fruK
1-phosphofructokinase (fructose-1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.996
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.639
manN
Mannose-specific phosphotransferase system, enzyme IID.
 
  
 0.579
LCA_1200
Putative trehalose and glucose-specific phosphotransferase system, enzyme IIBC.
 
  
 0.577
budC
Acetoin reductase (acetoin dehydrogenase) (Meso-2,3-butanediol dehydrogenase).
 
  
 0.550
nagE
N-acetylglucosamine and glucose-specific phosphotransferase system, enzyme IIABC.
  
  
 0.523
LCA_1198
Putative trehalose and glucose-specific phosphotransferase system, enzyme EIIA.
  
  
 0.523
scrA
Sucrose-specific phosphotransferase system, enzyme IIBCA.
  
  
 0.523
adhE
Bifunctional enzyme: alcohol dehydrogenase, acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.522
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
Server load: low (26%) [HD]