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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_1215Two component system, response regulator. (246 aa)    
Predicted Functional Partners:
LCA_1214
Two-component system, sensor histidine kinase.
 
 0.977
LCA_1383
Two-component system, sensor histidine kinase.
 
 0.891
LCA_0278
Two-component system, sensor histidine kinase.
 
 0.890
LCA_0501
Two-component system, sensor histidine kinase (possibly involved in phosphate regulation).
 
 0.878
LCA_0078
Two-component system, sensor histidine kinase.
 
 0.831
LCA_1455
Two-component system, sensor histidine kinase.
 
 0.773
LCA_1057
Putative amino acid ABC transporter, substrate binding/permease subunit.
  
   
 0.452
LCA_1216
6 Protein of unknown function, without similarity to other proteins.
       0.448
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.