Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCA_1409Hypothetical cell surface protein precursor. (353 aa)    
Predicted Functional Partners:
ftsX
Cell-division associated ABC transporter, membrane FtsX subunit; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.676
LCA_1076
Hypothetical extracellular protein precursor.
 
    0.636
ftsE
Cell-division associated ABC transporter, ATP binding FtsE subunit; Part of the ABC transporter FtsEX involved in cellular division.
 
  
 0.613
LCA_1788
Putative phage-related 1,4-beta-N-acetyl muramidase (cell wall hydrolase).
   
  
 0.577
LCA_0106
Hypothetical cell surface protein precursor.
 
  
 0.516
metS
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.499
LCA_0692
Putative serine/threonine protein kinase.
 
   
 0.464
smpB
t/mRNA binding protein (SsrA RNA binding protein); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. [...]
       0.444
LCA_1078
5 Proteins of unknown function that are similar to other proteins; Belongs to the UPF0358 family.
  
     0.437
rexAC
ATP-dependent exonuclease, subunit A (C terminal fragment), authentic frameshift.
  
     0.420
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.