STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_1476Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (367 aa)    
Predicted Functional Partners:
recX
Putative regulatory protein, RecX family; Modulates RecA activity; Belongs to the RecX family.
    
 0.944
LCA_1475
5 Proteins of unknown function that are similar to other proteins; Belongs to the UPF0374 family.
      0.866
exoA
Exodeoxyribonuclease III.
    
 0.840
LCA_1478
6 Protein of unknown function, without similarity to other proteins.
       0.773
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
  
 0.575
dnaN
DNA-directed DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for [...]
   
 
 0.573
recJ
Single-strand DNA-specific exonuclease RecJ.
      
 0.550
nth
Putative DNA repair protein, endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
  
0.469
birA1
Biotin-[acetyl-CoA carboxylase] ligase.
  
  
 0.445
birA2
Biotin-[acetyl-CoA-carboxylase] ligase.
  
  
 0.445
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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