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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCA_1698Hypothetical integral membrane protein. (233 aa)    
Predicted Functional Partners:
mntH2
Mn(2+)/Fe(2+) transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
       0.633
LCA_1704
Putative calcium-transporting P-type ATPase.
  
 
 0.615
LCA_1568
Putative calcium-transporting P-type ATPase.
  
 
 0.561
LCA_0208
Hypothetical integral membrane protein.
  
  
 0.523
LCA_0525
Hypothetical integral membrane protein.
  
  
 0.523
LCA_1697
Putative amino-acid/polyamine transport protein.
  
    0.498
ftsH
ATP-dependent zinc metalloendopeptidase FtsH (cell division protein FtsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.455
atpB
H(+)-transporting two-sector ATPase (ATP synthase), A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
    
 
 0.433
LCA_0406
Putative nucleoside triphosphatase, Ham1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.410
Your Current Organism:
Lactobacillus sakei
NCBI taxonomy Id: 314315
Other names: L. sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei 23K, Lactobacillus sakei subsp. sakei str. 23K, Lactobacillus sakei subsp. sakei strain 23K
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