Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
KON48402.1Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)    
Predicted Functional Partners:
KON48490.1
Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.923
KON48403.1
Phosphopantothenoylcysteine synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
    
  0.782
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
   0.726
KON47593.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
      
 0.704
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.699
KON48095.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.653
KON47114.1
Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.625
KON48157.1
Cytochrome C peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.619
KON47175.1
Methylamine utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.619
KON46747.1
Flagellar biosynthesis protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family.
    
   0.582
Your Current Organism:
Mariprofundus ferrooxydans
NCBI taxonomy Id: 314344
Other names: DSM 23021, M. ferrooxydans, Mariprofundus ferrooxydans Emerson et al. 2010, Siderooxidans marinum, strain PV-1
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