STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KON46736.1Ribosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)    
Predicted Functional Partners:
KON46737.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family.
       0.773
nadD
Nicotinate-nucleotide adenylyltransferase-like protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.765
rsfS
Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.556
KON46738.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.519
KON46739.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.519
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.503
KON46735.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.497
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.480
hisS
histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.460
KON46633.1
Sun protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
  
 0.422
Your Current Organism:
Mariprofundus ferrooxydans
NCBI taxonomy Id: 314344
Other names: DSM 23021, M. ferrooxydans, Mariprofundus ferrooxydans Emerson et al. 2010, Siderooxidans marinum, strain PV-1
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