node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KB13_1238 | folB | KB13_1238 | KB13_108 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | [H] COG1539 Dihydroneopterin aldolase. | 0.454 |
KB13_1238 | folK | KB13_1238 | KB13_254 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.539 |
KB13_1238 | folP | KB13_1238 | KB13_977 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.455 |
KB13_1238 | ribD | KB13_1238 | KB13_760 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.473 |
KB13_278 | folB | KB13_278 | KB13_108 | Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases. | [H] COG1539 Dihydroneopterin aldolase. | 0.507 |
KB13_278 | folK | KB13_278 | KB13_254 | Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.968 |
KB13_777 | folB | KB13_777 | KB13_108 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | [H] COG1539 Dihydroneopterin aldolase. | 0.538 |
folB | KB13_1238 | KB13_108 | KB13_1238 | [H] COG1539 Dihydroneopterin aldolase. | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.454 |
folB | KB13_278 | KB13_108 | KB13_278 | [H] COG1539 Dihydroneopterin aldolase. | Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases. | 0.507 |
folB | KB13_777 | KB13_108 | KB13_777 | [H] COG1539 Dihydroneopterin aldolase. | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | 0.538 |
folB | folC | KB13_108 | KB13_1020 | [H] COG1539 Dihydroneopterin aldolase. | [H] COG0285 Folylpolyglutamate synthase. | 0.775 |
folB | folE2 | KB13_108 | KB13_922 | [H] COG1539 Dihydroneopterin aldolase. | Conserved hypothetical protein TIGR00294; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.586 |
folB | folK | KB13_108 | KB13_254 | [H] COG1539 Dihydroneopterin aldolase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.981 |
folB | folP | KB13_108 | KB13_977 | [H] COG1539 Dihydroneopterin aldolase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.964 |
folB | plsY | KB13_108 | KB13_1135 | [H] COG1539 Dihydroneopterin aldolase. | Conserved hypothetical protein TIGR00023; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.608 |
folB | queD | KB13_108 | KB13_480 | [H] COG1539 Dihydroneopterin aldolase. | Queuosine biosynthesis protein QueD; [H] COG0720 6-pyruvoyl-tetrahydropterin synthase. | 0.639 |
folB | ribD | KB13_108 | KB13_760 | [H] COG1539 Dihydroneopterin aldolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.473 |
folC | folB | KB13_1020 | KB13_108 | [H] COG0285 Folylpolyglutamate synthase. | [H] COG1539 Dihydroneopterin aldolase. | 0.775 |
folC | folK | KB13_1020 | KB13_254 | [H] COG0285 Folylpolyglutamate synthase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.880 |
folC | folP | KB13_1020 | KB13_977 | [H] COG0285 Folylpolyglutamate synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |