Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ahpCPeroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (188 aa)    
Predicted Functional Partners:
ahpF
Alkyl hydroperoxide reductase, F subunit; [O] COG0492 Thioredoxin reductase.
 
  
 0.975
KB13_919
Redoxin superfamily protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.881
trxB
Thioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.807
fur
Leucine-rich repeat:Ferric uptake regulator family protein; [P] COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
  
 0.698
lpdA
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
   
 0.662
KB13_869
[O] COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family.
    
 0.595
trxA
[O] COG3118 Thioredoxin domain-containing protein.
    
 
 0.570
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 
 0.565
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.565
KB13_498
Peptidase M48, Ste24p; [R] COG4783 Putative Zn-dependent protease, contains TPR repeats.
       0.519
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
Server load: low (12%) [HD]