STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrCHypothetical protein; [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; probable Secreted protein-methione-sulfoxide reductase with methionine-s-sulfoxide and methionine-r-sulfoxide reductase activity putative signal peptide msyqgliylssvailfsassva; EC_number=1.8.4.11. (236 aa)    
Predicted Functional Partners:
dsbD
Thiol:disulfide interchange protein DsbD; [O] COG0785 Cytochrome c biogenesis protein.
   
 
 0.999
KB13_919
Redoxin superfamily protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.998
msrA
methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.891
grxC
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.839
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
    
   0.838
KB13_195
Conserved hypothetical protein; [J] COG0227 Ribosomal protein L28.
    
   0.838
rpsP
[J] COG2058 Ribosomal protein L12E/L44/L45/RPP1/RPP2; Belongs to the bacterial ribosomal protein bS16 family.
    
   0.838
rpmG
[J] COG0267 Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.838
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.823
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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