| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_129 | KB13_777 | KB13_129 | KB13_777 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | 0.843 |
| KB13_129 | KB13_862 | KB13_129 | KB13_862 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [P] COG0569 K+ transport systems, NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.790 |
| KB13_129 | alr | KB13_129 | KB13_1024 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.674 |
| KB13_129 | dhaL | KB13_129 | KB13_677 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.546 |
| KB13_129 | gltB | KB13_129 | KB13_763 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3. | 0.895 |
| KB13_129 | glyA | KB13_129 | KB13_542 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.568 |
| KB13_129 | lpdA | KB13_129 | KB13_169 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.868 |
| KB13_129 | metH | KB13_129 | KB13_806 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.813 |
| KB13_129 | thiG | KB13_129 | KB13_838 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.990 |
| KB13_129 | thiS | KB13_129 | KB13_1106 | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis. | 0.948 |
| KB13_777 | KB13_129 | KB13_777 | KB13_129 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.843 |
| KB13_777 | alr | KB13_777 | KB13_1024 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.513 |
| KB13_777 | dhaL | KB13_777 | KB13_677 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.897 |
| KB13_777 | gltB | KB13_777 | KB13_763 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3. | 0.906 |
| KB13_777 | glyA | KB13_777 | KB13_542 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.662 |
| KB13_777 | lpdA | KB13_777 | KB13_169 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.910 |
| KB13_777 | metH | KB13_777 | KB13_806 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.452 |
| KB13_862 | KB13_129 | KB13_862 | KB13_129 | [P] COG0569 K+ transport systems, NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.790 |
| KB13_862 | gltB | KB13_862 | KB13_763 | [P] COG0569 K+ transport systems, NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3. | 0.491 |
| KB13_862 | lpdA | KB13_862 | KB13_169 | [P] COG0569 K+ transport systems, NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.476 |