Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_170ATP:cob(I)alamin adenosyltransferase; [S] COG2096 Uncharacterized conserved protein; Belongs to the Cob(I)alamin adenosyltransferase family. (180 aa)    
Predicted Functional Partners:
pcnB
poly(A) polymerase; [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.782
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
       0.716
KB13_278
Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases.
       0.692
panB_1
[H] COG0413 Ketopantoate hydroxymethyltransferase.
       0.664
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.598
panC
Pantoate--beta-alanine ligase; [H] COG0414 Panthothenate synthetase; Belongs to the pantothenate synthetase family.
       0.519
KB13_934
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.496
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.428
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.406
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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