STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KB13_171[S] COG3737 Uncharacterized conserved protein. (117 aa)    
Predicted Functional Partners:
KB13_987
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.685
thrC
[E] COG0498 Threonine synthase.
       0.595
KB13_999
[E] COG0460 Homoserine dehydrogenase.
       0.595
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.557
KB13_853
Aminotransferase, class I and II; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
       0.557
folA
[H] COG0262 Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
       0.504
KB13_722
Conserved hypothetical protein; [QR] COG0500 SAM-dependent methyltransferases.
  
     0.470
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.