STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
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[Homology]
Score
KB13_180[T] COG0642 Signal transduction histidine kinase. (696 aa)    
Predicted Functional Partners:
KB13_1057
Two component, sigma54 specific, transcriptional regulator, Fis family; [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 
 0.980
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
 
  
 0.907
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.842
ntrC
Nitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
  
 0.813
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
     
 0.809
KB13_1082
Hypothetical protein.
       0.773
KB13_276
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.679
KB13_301
Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
    
 0.657
KB13_1159
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.656
KB13_1253
Stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
    
  0.607
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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