Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBThioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (313 aa)    
Predicted Functional Partners:
trxA
[O] COG3118 Thioredoxin domain-containing protein.
  
 0.928
KB13_919
Redoxin superfamily protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.928
KB13_468
Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 0.873
gltB
Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.
    
  0.829
KB13_928
Smr protein/MutS2; [S] COG2840 Uncharacterized protein conserved in bacteria.
       0.817
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.807
KB13_804
CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase; [C] COG0633 Ferredoxin.
   
 0.805
KB13_958
Hypothetical protein.
  
 0.790
lpdA
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 0.785
KB13_714
Peroxidase; [O] COG1225 Peroxiredoxin.
  
 
 0.760
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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