STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_207[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. (541 aa)    
Predicted Functional Partners:
KB13_301
Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.991
KB13_1036
Two component transcriptional regulator, LuxR family; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 0.989
KB13_1159
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.954
KB13_276
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.944
KB13_1057
Two component, sigma54 specific, transcriptional regulator, Fis family; [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 
 0.922
phoR
Phosphate regulon sensor protein; [T] COG0642 Signal transduction histidine kinase.
 
 
 0.914
KB13_1253
Stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
   
 0.912
ntrC
Nitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
   
 0.909
KB13_180
[T] COG0642 Signal transduction histidine kinase.
 
  
 0.907
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
 
 
 0.906
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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