Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_215[R] COG0637 Predicted phosphatase/phosphohexomutase. (224 aa)    
Predicted Functional Partners:
rpe
[G] COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.963
KB13_777
Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase.
    
 0.862
KB13_845
[R] COG0546 Predicted phosphatases.
  
  
 
0.848
KB13_916
HAD-superfamily hydrolase; [R] COG0546 Predicted phosphatases.
  
  
 
0.846
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
       0.817
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
       0.791
KB13_701
Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit.
       0.791
trpC
[E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
       0.791
KB13_1198
P-protein; [E] COG1605 Chorismate mutase.
  
 
  0.785
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
  0.767
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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