Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amiCN-acetylmuramoyl-l-alanine amidase, amic protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase. (413 aa)    
Predicted Functional Partners:
KB13_625
Peptidase M23B; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
 
   0.912
KB13_611
Lytic transglycosylase, catalytic; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).
    
 0.889
KB13_636
Uncharacterised P-loop hydrolase UPF0079; [R] COG0802 Predicted ATPase or kinase.
  
   0.827
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.780
KB13_1303
Sporulation related; [D] COG3087 Cell division protein.
  
 0.751
lolA
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
    
   0.736
KB13_1171
[C] COG1600 Uncharacterized Fe-S protein; 4Fe-4S cluster binding.
       0.651
cpoB
Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
     
 0.530
KB13_201
Peptidase M23B; [D] COG4942 Membrane-bound metallopeptidase.
  
   
 0.519
KB13_511
Conserved hypothetical protein, putative; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
   
 0.514
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
Server load: low (10%) [HD]