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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
KB13_227Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. (199 aa)    
Predicted Functional Partners:
KB13_934
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
    
 0.792
KB13_99
[K] COG0782 Transcription elongation factor.
       0.792
KB13_1238
[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
  
    0.674
KB13_1092
ABC-2; [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.
  
    0.648
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 
 0.575
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.474
KB13_392
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
   
    0.474
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.449
KB13_259
Hydrolase, alpha/beta fold family, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
  0.430
KB13_191
[R] COG1988 Predicted membrane-bound metal-dependent hydrolases.
       0.417
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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