| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1092 | KB13_227 | KB13_1092 | KB13_227 | ABC-2; [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component. | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | 0.659 |
| KB13_1238 | KB13_227 | KB13_1238 | KB13_227 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | 0.565 |
| KB13_1238 | KB13_392 | KB13_1238 | KB13_392 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.542 |
| KB13_1238 | KB13_934 | KB13_1238 | KB13_934 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.499 |
| KB13_1238 | guaA | KB13_1238 | KB13_1251 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.499 |
| KB13_1238 | ribB | KB13_1238 | KB13_1236 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.488 |
| KB13_227 | KB13_1092 | KB13_227 | KB13_1092 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | ABC-2; [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component. | 0.659 |
| KB13_227 | KB13_1238 | KB13_227 | KB13_1238 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.565 |
| KB13_227 | KB13_259 | KB13_227 | KB13_259 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | Hydrolase, alpha/beta fold family, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.430 |
| KB13_227 | KB13_392 | KB13_227 | KB13_392 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.462 |
| KB13_227 | KB13_804 | KB13_227 | KB13_804 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase; [C] COG0633 Ferredoxin. | 0.460 |
| KB13_227 | KB13_934 | KB13_227 | KB13_934 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.889 |
| KB13_227 | KB13_99 | KB13_227 | KB13_99 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | [K] COG0782 Transcription elongation factor. | 0.817 |
| KB13_227 | guaA | KB13_227 | KB13_1251 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.613 |
| KB13_227 | metH | KB13_227 | KB13_806 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.423 |
| KB13_227 | ribB | KB13_227 | KB13_1236 | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.482 |
| KB13_259 | KB13_227 | KB13_259 | KB13_227 | Hydrolase, alpha/beta fold family, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | 0.430 |
| KB13_259 | guaA | KB13_259 | KB13_1251 | Hydrolase, alpha/beta fold family, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.810 |
| KB13_392 | KB13_1238 | KB13_392 | KB13_1238 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.542 |
| KB13_392 | KB13_227 | KB13_392 | KB13_227 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Putative NAD(P)H nitroreductase YdfN; [C] COG0778 Nitroreductase. | 0.462 |