Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_230Tetratricopeptide repeat domain protein; [R] COG0457 FOG: TPR repeat. (580 aa)    
Predicted Functional Partners:
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
   
  0.784
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.770
KB13_1061
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase, putative; [R] COG0457 FOG: TPR repeat.
 
 
  0.763
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
     
 0.735
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
   
  0.713
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
  0.710
KB13_251
O-linked GlcNAc transferase, putative; [R] COG0457 FOG: TPR repeat.
  
     0.697
KB13_55
[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
    
  0.688
KB13_1296
Hypothetical protein.
    
  0.683
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.672
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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