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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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KB13_233[P] COG1629 Outer membrane receptor proteins, mostly Fe transport. (725 aa)    
Predicted Functional Partners:
tolA
Protein TolA; [M] COG3064 Membrane protein involved in colicin uptake.
  
  0.745
KB13_1071
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
  0.736
KB13_1144
TonB family C-terminal domain protein; [M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
  
  0.714
KB13_1287
[P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
  
  
 0.704
mviN
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
     
 0.584
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.578
KB13_1311
Oxidoreductase, molybdopterin binding; [R] COG2041 Sulfite oxidase and related enzymes.
       0.578
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
       0.578
ribF
Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family.
       0.578
KB13_281
[S] COG0432 Uncharacterized conserved protein.
       0.568
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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