KB13_240 protein (beta proteobacterium KB13)

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KB13_240

Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (495 aa)

Predicted Functional Partners:

sdhA

0.993

sdhB

0.987

KB13_42

0.968

sdhD

0.965

prpC

0.963

sdhC

0.960

gltA

0.953

KB13_405

0.951

maeB

0.945

sucC

0.919

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_240	KB13_405	KB13_240	KB13_405	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	0.951
KB13_240	KB13_42	KB13_240	KB13_42	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Putative HpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.	0.968
KB13_240	gltA	KB13_240	KB13_992	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.	0.953
KB13_240	maeB	KB13_240	KB13_303	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Bifunctional protein: malate dehydrogenase phosphotransacetylase; [C] COG0281 Malic enzyme.	0.945
KB13_240	prpC	KB13_240	KB13_95	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.	0.963
KB13_240	sdhA	KB13_240	KB13_608	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.993
KB13_240	sdhB	KB13_240	KB13_960	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	SdhB succinate dehydrogenase (iron-sulfur subunit) oxidoreductase protein; [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.987
KB13_240	sdhC	KB13_240	KB13_1062	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.960
KB13_240	sdhD	KB13_240	KB13_753	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	[C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	0.965
KB13_240	sucC	KB13_240	KB13_319	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.919
KB13_405	KB13_240	KB13_405	KB13_240	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.951
KB13_405	gltA	KB13_405	KB13_992	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.	0.855
KB13_405	maeB	KB13_405	KB13_303	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	Bifunctional protein: malate dehydrogenase phosphotransacetylase; [C] COG0281 Malic enzyme.	0.577
KB13_405	prpC	KB13_405	KB13_95	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.	0.855
KB13_405	sdhA	KB13_405	KB13_608	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.847
KB13_405	sdhB	KB13_405	KB13_960	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	SdhB succinate dehydrogenase (iron-sulfur subunit) oxidoreductase protein; [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.777
KB13_405	sucC	KB13_405	KB13_319	Isocitrate Dehydrogenase (Mutant With Ser 113 Replaced By Asp) (S113D); [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase.	succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.927
KB13_42	KB13_240	KB13_42	KB13_240	Putative HpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.968
KB13_42	maeB	KB13_42	KB13_303	Putative HpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.	Bifunctional protein: malate dehydrogenase phosphotransacetylase; [C] COG0281 Malic enzyme.	0.682
KB13_42	sdhA	KB13_42	KB13_608	Putative HpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.	[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.594