Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (149 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folB
[H] COG1539 Dihydroneopterin aldolase.
  
 
 0.983
KB13_278
Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases.
      0.971
pcnB
poly(A) polymerase; [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
    0.971
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.896
folE2
Conserved hypothetical protein TIGR00294; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.883
folC
[H] COG0285 Folylpolyglutamate synthase.
 
 0.873
KB13_1198
P-protein; [E] COG1605 Chorismate mutase.
      0.863
panB_1
[H] COG0413 Ketopantoate hydroxymethyltransferase.
 
 
 0.827
panC
Pantoate--beta-alanine ligase; [H] COG0414 Panthothenate synthetase; Belongs to the pantothenate synthetase family.
 
   
 0.718
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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