Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KB13_272Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (357 aa)    
Predicted Functional Partners:
KB13_585
Acriflavin resistance protein; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.997
KB13_737
Type I secretion outer membrane protein, TolC; [MU] COG1538 Outer membrane protein.
 
 0.979
KB13_978
[MU] COG1538 Outer membrane protein.
 
 0.860
KB13_826
Acriflavin resistance protein; [P] COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.854
czcA
Cation efflux system protein CzcA; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.820
KB13_375
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.
       0.773
KB13_369
Hypothetical protein.
   
  0.672
lolD
Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
  
 
 0.643
KB13_404
Hypothetical protein.
       0.506
KB13_811
Conserved hypothetical protein; [S] COG1714 Predicted membrane protein/domain.
       0.499
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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